蟾毒靈
分析標(biāo)準(zhǔn)品,HPLC≥98%
Bufalin
CAS號：465-21-4
分子式： C24H34O4
分子量：386.53
MDL：MFCD00056525
貨號 | 規(guī)格/參數(shù)/品牌 | 價格 | 貨期 |
YJ-B20152-5mg | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥600.00 | 現(xiàn)貨 |
YJ-B20152-20mg | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥1020.00 | 現(xiàn)貨 |
YJ-B20152-100mg | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥2980.00 | 現(xiàn)貨 |
產(chǎn)品介紹
熔點(diǎn)：242-243℃
沸點(diǎn)：556.6 ℃ at 760 mmHg
比旋光度：D -20°
外觀：針狀晶體
溶解性：DMSO : 100 mg/mL (258.72 mM; Need ultrasonic)
儲存條件：2-8℃
注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。
參考文獻(xiàn)(33篇)
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27. [IF=4.8] Zijun Qian et al."Bufalin inhibits the proliferation of lung cancer cells by suppressing Hippo-YAP pathway."CELLULAR SIGNALLING.2023 Sep;109:110746
26. [IF=1.902] Ke-ke Cui et al."Quantitative analysis of multicomponents by a single marker and quality evaluation of Venenum Bufonis from different geographical origins."Biomed Chromatogr. 2019 Sep;33(9):e4555
25. [IF=3.565] Liqiang Qian et al."Anti-tumor Activity of Bufalin by Inhibiting c-MET Mediated MEK/ERK and PI3K/AKT Signaling Pathways in Gallbladder Cancer."J Cancer. 2020; 11(11): 3114–3123
24. [IF=4.379] Cao Yueting et al."The impact of multiple climatic and geographic factors on the chemical defences of Asian toads (Bufo gargarizans Cantor)."Sci Rep-Uk. 2019 Nov;9(1):1-11
23. [IF=4.411] Yueting Cao et al."Chemical Profile and Multicomponent Quantitative Analysis for the Quality Evaluation of Toad Venom from Different Origins."Molecules. 2019 Jan;24(19):3595
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20. [IF=2.311] Jinlin Xie et al."Bufalin suppresses the proliferation and metastasis of renal cell carcinoma by inhibiting the PI3K/Akt/mTOR signaling pathway."Oncol Lett. 2018 Sep;16(3):3867-3873
19. [IF=2.748] Tao Song et al."Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, suppresses hERG K+ currents expressed in HEK293 cells."Fund Clin Pharmacol. 2017 Dec;31(6):695-700
18. [IF=2.748] Tao Song et al."Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, inhibits L-type Ca2+ channels and contractility in rat ventricular myocytes."Fund Clin Pharmacol. 2017 Jun;31(3):340-346
17. [IF=3.743] Yu-Long Lan et al."Bufalin inhibits glioblastoma growth by promoting proteasomal degradation of the Na+/K+-ATPase α1 subunit."Biomed Pharmacother. 2018 Jul;103:204
16. [IF=4.101] Yao Liu et al."Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice."Int J Mol Med. 2017 Aug;40(2):357-366
15. [IF=6.284] Lan Yu-Long et al."The sodium pump α1 subunit regulates bufalin sensitivity of human glioblastoma cells through the p53 signaling pathway."Cell Biol Toxicol. 2019 Dec;35(6):521-539
14. Haiyan Hu, Qi Qi, Ziyi Dong, Xianglong Yu, Yujia Mo, Juyuan Luo, Yan Wang, Shouying Du, Yang Lu,
Albumin coated trimethyl chitosan-based targeting delivery platform for photothermal/chemo-synergistic cancer therapy,
Carbohydrate Polymers,
Volume 241,
2020,
13. Xie, Jinlin, et al. "Bufalin suppresses the proliferation and metastasis of renal cell carcinoma by inhibiting the PI3K/Akt/mTOR signaling pathway." Oncology letters 16.3 (2018): 3867-3873.https:##doi.org/10.3892/ol.2018.9111
12. Song, Tao, et al. "Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, inhibits L‐type Ca2+ channels and contractility in rat ventricular myocytes." Fundamental & clinical pharmacology 31.3 (2017): 340-346.https:##doi.org/10.1111/fc
11. Song, Tao, et al. "Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, suppresses hERG K+ currents expressed in HEK 293 cells." Fundamental & clinical pharmacology 31.6 (2017): 695-700.https:##doi.org/10.1111/fcp.12306
10. Liu, Yao, et al. "Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice." International journal of molecular medicine 40.2 (2017): 357-366. https:##doi.org/10.3892/ijmm.2017.3039
9. Liu, Yao, et al. "Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice." International journal of molecular medicine 40.2 (2017): 357-366. https:##doi.org/10.3892/ijmm.2017.3039
8. 曹月婷 崔可可 吳紀(jì)恒 等. 中華大蟾蜍毒液中蟾毒配基類成分的相關(guān)性研究[J]. 中國中藥雜志 2019(9).
7. 房蘊(yùn)歌, 王鵬飛, 朱厚達(dá),等. 蟾酥藥材和飲片(蟾酥粉)的質(zhì)量標(biāo)準(zhǔn)研究[J]. 中國中藥雜志, 2020(8).
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5. 田志輝, 張培, 曹彥坤,等. 蟾蜍靈抑制食管癌細(xì)胞增殖、遷移和趨化運(yùn)動的機(jī)制研究[J]. 中國現(xiàn)代醫(yī)學(xué)雜志, 2015(20):50-54.
4. 丁妍,王小玲,鄧會巖,蘇麗宏,張培,劉月平.蟾蜍靈抑制Raf/MEK/細(xì)胞外信號調(diào)節(jié)激酶信號通路活化影響人食管鱗癌細(xì)胞增殖及遷移機(jī)制研究[J].中國全科醫(yī)學(xué),2015,18(21):2535-2541.
3. 陳硯凝, 劉堯, 王小玲,等. 蟾蜍令靈對裸鼠食管鱗癌原位移植瘤中 P70S6K 表達(dá)的影響[J]. 中國全科醫(yī)學(xué), 2015(15期):1763-1767.
2. 張玲玲 韓金薇 王曉琳 et al. Bufalin抑制食管癌TE13細(xì)胞遷移機(jī)制探討[J]. 中華腫瘤防治雜志 2016 23(13):837-843.
1. 丁妍 王小玲 柳慧 等. Bufalin促進(jìn)人食管癌細(xì)胞ECA109凋亡的研究[J]. 食管外科電子雜志 2014(02):49-54.
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