落新婦苷
分析標準品,HPLC≥98%
Astilbin
CAS號：29838-67-3
分子式：C21H22O11
分子量：450.4
MDL：MFCD20274680
貨號 | 規格/參數/品牌 | 價格 | 貨期 |
YJ-B20812-20mg | 分析標準品,HPLC≥98% | ￥350.00 | 現貨 |
YJ-B20812-1g | 分析標準品,HPLC≥98% | ￥3580.00 | 現貨 |
產品介紹
熔點：180 ℃ (decomp)
沸點：801.1 oC at 760 mmHg
外觀：無色晶體
溶解性：DMSO：50mg/ml
儲存條件：2-8℃
注意：部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。
參考文獻(37篇)
37. [IF=4.8] Haixing Feng et al."Astilbin from Smilax china L. remarkably inhibits LPS-induced endometritis in rats via blocking positive feedback between TLR4 and IL-6R signalling pathways in a PPAR-γ-dependent manner."JOURNAL OF ETHNOPHARMACOLOGY.2025 Apr;:119861
36. [IF=4.7] Zhengyao Yu et al."Exploring the Therapeutic and Gut Microbiota-Modulating Effects of Qingreliangxuefang on IMQ-Induced Psoriasis."Drug Design Development and Therapy.
35. [IF=6.8] Guangliang Shi et al."The antagonism mechanism of astilbin against cadmium-induced injury in chicken lungs via Treg/Th1 balance signaling pathway."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY".2024 Jun;277:116364
34. [IF=5.4] Yingxue Guo et al."Integrated network pharmacological analysis revealed that Smilax glabra Roxb. alleviates IMQ-induced psoriatic skin inflammation through regulating T cell immune response."JOURNAL OF ETHNOPHARMACOLOGY".2024 May;325:117836
33. [IF=6.8] Yue Zhu et al."Astilbin antagonizes developmental cardiotoxicity after cadmium exposure in chicken embryos by inhibiting endoplasmic reticulum stress and maintaining calcium homeostasis."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.2024 Jan;270:115847
32. [IF=7.2] Zhao Fang et al."Astilbin protects from sepsis-induced cardiac injury through the NRF2/HO-1 and TLR4/NF-κB pathway."PHYTOTHERAPY RESEARCH.2023 Dec;:
31. [IF=5.4] Mingxiang Xie et al."Molecular mechanism of PSORI-CM01 for psoriasis by regulating the inflammatory cytokines network."JOURNAL OF ETHNOPHARMACOLOGY.2024 Jan;318:116935
30. [IF=6.656] Chong Chen et al."Yishen-Qingli-Huoxue Formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling."PHYTOMEDICINE.2022 Nov;:154546
29. [IF=5.396] Tingwei Wang et al."Astilbin from Smilax glabra Roxb. alleviates high-fat diet-induced metabolic dysfunction."Food Funct. 2022 Apr;:
28. [IF=1.216] Han Yan et al."Studies on the Anti-Gouty Arthritis and Anti-hyperuricemia Properties of Astilbin in Animal Models."Open Chem. 2020 Jan;18(1):207-214
27. [IF=3.297] Mao Yang et al."Astilbin influences the progression of osteoarthritis in rats by down-regulation of PGE-2 expression via the NF-κB pathway."Ann Transl Med. 2020 Jun; 8(12): 766
26. [IF=3.69] Qianni Duan et al."Antiviral effect of Chinese herbal prescription JieZe-1 on adhesion and penetration of VK2/E6E7 with herpes simplex viruses type 2."J Ethnopharmacol. 2020 Mar;249:112405
25. [IF=4.225] Wen Xianghui et al."Qu-Zhuo-Tong-Bi Decoction Alleviates Gouty Arthritis by Regulating Butyrate-Producing Bacteria in Mice."Front Pharmacol. 2021 Feb;11:2508
24. [IF=6.529] Xue Chen et al."Dendrobium officinalis six nostrum ameliorates urate under-excretion and protects renal dysfunction in lipid emulsion-induced hyperuricemic rats."Biomed Pharmacother. 2020 Dec;132:110765
23. [IF=2.398] Hui Bi et al."Analgesic effects of astilbin partially via calcium channels through regulation on CaMKII."Food Agr Immunol. 2019;30(1):309-319
22. [IF=3.775] Si-wei Wang et al."Astilbin ameliorates cisplatin-induced nephrotoxicity through reducing oxidative stress and inflammation."Food Chem Toxicol. 2018 Apr;114:227
21. [IF=3.906] Xiaoqi Sun et al."Caspase-dependent mitochondrial apoptotic pathway is involved in astilbin-mediated cytotoxicity in breast carcinoma cells."Oncol Rep. 2018 Oct;40(4):2278-2286
20. [IF=4.36] Yueqin Cai et al."Medicinal effect and its JP2/RyR2-based mechanism of Smilax glabra flavonoids on angiotensin II-induced hypertrophy model of cardiomyocytes."J Ethnopharmacol. 2015 Jul;169:435
19. Duan, Qianni, et al. "Antiviral effect of Chinese herbal prescription JieZe-1 on adhesion and penetration of VK2/E6E7 with herpes simplex viruses type 2." Journal of ethnopharmacology 249 (2020): 112405.https:##doi.org/10.1016/j.jep.2019.112405
18. Hui Bi, Zhen Sun, Qiubo Chu, Lanzhou Li, Xin Guan, Yulin Zhou & Zhiwen Li (2019) Analgesic effects of astilbin partially via calcium channels through regulation on CaMKII, Food and Agricultural Immunology, 30:1, 309-319, DOI: 10.1080/09540105.2019.1580677
17. Wang, Si-wei, et al. "Astilbin ameliorates cisplatin-induced nephrotoxicity through reducing oxidative stress and inflammation." Food and chemical toxicology 114 (2018): 227-236.https:##doi.org/10.1016/j.fct.2018.02.041
16. Yang, Mao, et al. "Astilbin influences the progression of osteoarthritis in rats by down-regulation of PGE-2 expression via the NF-κB pathway." Annals of Translational Medicine 8.12 (2020).https:##dx.doi.org/10.21037%2Fatm-20-4485
15. Sun, Xiaoqi, et al. "Caspase-dependent mitochondrial apoptotic pathway is involved in astilbin-mediated cytotoxicity in breast carcinoma cells." Oncology reports 40.4 (2018): 2278-2286.https:##doi.org/10.3892/or.2018.6602
14. 王夢雪,戴寒鵬,李金明,蘇婭,韓欣然,李麗.土茯苓抑制CYP3A4酶活性的研究[J].長春師范大學學報,2020,39(08):60-63.
13. 馮麗敏, 趙瑞芝, 王銀潔,等. 正交設計法優選銀屑靈片中腫節風有效成分的提取工藝[J]. 時珍國醫國藥, 2011(08):1860-1861.
12. 趙瑞芝,王銀潔,馮麗敏,盧傳堅.大鼠口服芍苓消銀片后血液中芍藥苷、落新婦苷、迷迭香酸、異嗪皮啶、甘草苷的藥物動力學研究[J].中國中藥雜志,2014,39(13):2559-2563.
11. 楊俊杰,張艷玲,王崢濤,陸兔林.土茯苓產地加工過程中去皮的合理性分析[J].中國實驗方劑學雜志,2017,23(03):1-5.
10. 楊俊杰, 黃紫炎, 李林,等. 土茯苓產地加工與炮制一體化工藝優選[J]. 時珍國醫國藥, 2018, 29(09):2165-2168.
9. 潘馨 衷林清 周楚楚 等. HPLC同時測定草珊瑚中9個有效成分的含量[J]. 藥物分析雜志 2017 037(007):1207-1214.
8. 馮麗敏 趙瑞芝 盧傳堅. HPLC同時測定芍苓消銀片中芍藥苷 落新婦苷 綠原酸 迷迭香酸和甘草酸的含量[J]. 中國現代應用藥學 2014 031(009):1097-1101.
7. 鄒靜 陳慧 彭懿 等. HPLC法同時測定加味二妙顆粒中7種成分及指紋圖譜建立[J]. 中成藥 2018 v.40(02):99-104.
6. 王銀潔, 趙瑞芝, 盧傳堅. 銀屑靈與土茯苓中落新婦苷大鼠體內的藥代動力學比較[J]. 中國中藥雜志, 2012, 37(12):1859-1861.
5. 徐萍,張淼,徐玉彬,毛旭南,張培建.落新婦苷預處理對大鼠肝臟缺血再灌注損傷和Bcl-2、Bax表達的影響[J].中國藥師,2016,19(11):2055-2058.
4. 黃慧輝, 張小燕, 沈娟,等. 菝葜抗炎有效部位群在大鼠腸外翻試驗中的吸收特性考察[J]. 中國實驗方劑學雜志, 2016, v.22(08):96-99.
3. 趙瑞芝, 史長燦, 劉麗娟,等. 芍苓消銀緩釋片Beagle犬體內藥物動力學評價[J]. 中國醫院藥學雜志, 2017, 11(v.37):17-19.
2. 王思為, 張峰, 鄭曉燕,等. 土茯苓活性分子落新婦苷聯合順鉑對人肺癌A549細胞凋亡的影響[J]. 中藥材, 2017(12).
1. 姜宣羽, 王思為, 樓麗君,等. 土茯苓活性分子落新婦苷抗順鉑誘導的人腎小管上皮細胞凋亡作用研究[J]. 浙江中西醫結合雜志, 2018, 28(09):735-738.
